Comparisons
Direct comparisons between products and molecules, grounded in the published trial evidence — including the SURMOUNT-5 head-to-head and the branded-vs-compounded landscape.
4 articles
Comparisons
Tirzepatide vs. semaglutide for heart health: what a real-world study of 297,842 patients found
A Nature Medicine study of 297,842 patients found comparable cardiovascular outcomes for tirzepatide vs. semaglutide. What that means and what it doesn't.
5 min · Updated 2026-05-28
Comparisons
Branded vs compounded GLP-1s, explained
Cost, legality, and oversight differ between brand-name GLP-1s and their compounded counterparts. Here's a structured way to think about the trade-offs.
12 min · Updated 2026-05-27
Comparisons
Tirzepatide vs. semaglutide: what the SURMOUNT-5 head-to-head trial actually showed
SURMOUNT-5 was the first head-to-head RCT comparing tirzepatide and semaglutide. Tirzepatide produced 20.2% vs 13.7% average weight loss at 72 weeks. Here's what those numbers mean — and don't mean.
3 min · Updated 2026-05-27
Comparisons
Semaglutide vs retatrutide: what we know so far
How semaglutide and retatrutide compare on mechanism, evidence, availability, and what is actually known about them in 2025.
7 min · Updated 2026-05-27